Regenerative Medicine: The road to healing

To identify and assess trends in regenerative medicine at an early stage, Fresenius Medical Care relies on a combination of in-house research and external investment. Cooperation with innovative start-ups is a key element of this strategy. To this end, the Company established Fresenius Medical Care Ventures in 2016, a venture capital fund that has set its strategic focus on investments in the regenerative medicine sector.

Both sides benefit from these strategic investments and alliances: Whereas the start-ups bring fresh ideas, agile structures and innovative technologies to the table, Fresenius Medical Care contributes its experience in the health care industry, global relationships, and market access. “We know how to bring new products successfully to market in the different health care systems,” says Schermeier. “In addition, we have a great deal of experience when it comes to developing a prototype through to series production.”

A bridge between research and therapy

Fresenius Medical Care Ventures is constantly on the lookout for promising partners and investment opportunities. Fresenius Medical Care has also pooled its research activities in the field of regenerative medicine internally. In 2016, Fresenius Medical Care unveiled a new subsidiary, Unicyte AG, the result of long-term collaboration with the University of Turin in Italy. It was born from the idea that pioneering research results should not only be published in scientific publications, but also benefit patients as quickly as possible. “We wanted to build a bridge from academic research to developing actual therapies quickly,” says Schermeier.

Unicyte AG is an independent subsidiary of Fresenius Medical Care. The Swiss-based biotech company operates in the field of regenerative medicine, focusing on kidney and liver diseases as well as oncology and diabetes.

Gradual evolution

The first research results from Unicyte AG are promising: In a pre-clinical model with mice suffering from rapidly advancing kidney disease, their kidney function was almost fully restored. Particles derived from stem cells, so-called nanoscale extracellular vesicles, prevented scarring of the mice’s kidney tissue. In another project, insulin-producing islet cells were grown in the laboratory.

“We see this as a promising field for treating diabetes in the future,” says Schermeier. So how close is the vision of regenerative medicine? “We could see therapy options that will enable us to fully restore our patients’ kidney function in as little as twenty years,” according to Schermeier. However, he believes that a sudden revolution is unlikely. “It will be a very gradual evolution that will improve our patients’ lives in the long term, and hopefully extend them, too.”