Individualized Sodium Management with the 6008 CAREsystem

Individualized Sodium Management with the 6008 CAREsystem allows for a diffusive sodium balance thanks to a closed-circuit control.


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Patients’ predialysis serum sodium is widely spread1

Guidelines strongly recommend an individualized dialysate sodium4,5

Sodium loading during HD clearly results in greater thirst with resultant volume expansion, increased cardiac workload and subsequent hypertension.4

There is evidence to suggest that high dietary sodium intake and inadequate sodium removal during HD can result in excess fluid intake and hypertension.

Individualizing dialysate sodium to the plasma sodium concentration may improve hemodynamic stability during dialysis.5

Easy alignment of dialysate sodium with plasma sodium concentration

Principle of continuous balancing of diffusive sodium transfer with individualized Sodium Management
Continuous balancing of diffusive sodium transfer

Information about patients’ salt intake enhances nutritional education

The trend of predialysis plasma sodium may indicate pathologic changes

Benefits of the easy and individualized Sodium Management with the 6008 CAREsystem

Distribution of plasma sodium changes

Sodium Management video

Sodium Management — a new therapy feature available with the 6008 CAREsystem

Prof. Bernard Canaud
Emeritus Professor of Nephrology | Montpellier University, France
Chief Medical Scientist | Global Medical Office EMEA

Sodium management symposium videos

56th ERA-EDTA Congress 2019

Present and future of sodium and water handling to improve outcomes in ESKD patients

Three experts presented different aspects of fluid management in hemodialysis therapies at the sodium management symposium (ERA-EDTA Congress 2019). 

Watch the symposium videos

Related content

1. Lindley EJ, Reducing sodium intake in hemodialysis patients. Semin Dial. 2009 May-Jun;22(3):260-263.
2. Raimann JG, Thijssen S, Usvyat LA, et al., Sodium alignment in clinical practiceimplementation and implications. Semin Dial. 2011;24:587–592.
3. Sagova et al., Automated individualization of dialysate sodium concentration reduces intradialytic plasma sodium changes in hemodialysis. Artif Organs. 2019 Oct; 43(10):1002-1013.
4. National Kidney Foundation, KDOQI clinical practice guideline for hemodialysis adequacy: 2015 update. Am J Kidney Dis. 2015;66(5):884-930.
5. Kooman et al., EBPG guideline on haemodynamic instability Nephrol Dial Transplant 2007; 22 [Suppl 2]:ii22-ii44.
6. Canaud B et al., Sodium and water handling during hemodialysis: new pathophysiologic insights and management approaches for improving outcomes in end-stage kidney disease. Kidney International 2019;95:304.
7. Basile C, and Lomonte C., A neglected issue in dialysis practice: haemodialysate. Clin Kidney J. 2015;8:393–399.
8. Maierhofer A et al., EDTA-Poster 2019 FP546, “Conductivity based online estimation of predialytic plasma Na: clinical assessment”.
9. Canaud et al., Kidney International (2019) 95, 296-309.